Liquid forms of drugs, such as cough syrup, are subject to contamination with toxic substances. WHO and UNP UN are called to urgent measures in connection with a large -scale threat of contaminated drugs Healthcare World Health Organization (WHO) and UN Drug and Crime (UNP) Office published a joint report on a systemic threat to the public, especially children: pollution of medicines with toxic industrial chemicals, in particular diethylene glycol (DEG) and ethylene glycol (EG). These substances, used in the production of antifreeze and solvents, enter the drugs instead of safe pharmaceutical ingredients. The consequences – & nbsp; hundreds of preventive deaths, mainly among children. as the new report, such & nbsp; tragedies & nbsp; is not a series of isolated incidents, but reflect the systemic crisis – lack of control over the supply of excipient supplies that form the basis of most liquid forms drugs. 60 ~ h2 > scale of the problem 62 > cases of mass poisoning by such substances in the world Since 1937. For 90 years & nbsp; it was documented at least 25 incidents that entailed more than 1300 deaths. 62 ~~ 60 > 62 ~Only from 2022, WHO released nine & nbsp; global warnings about medical products. In four cases, severe consequences were recorded: more than 300 deaths, including 200 in Indonesia, 68 in Uzbekistan & nbsp; and 66 in gambia. ~ 60 >~ 60 > case in Uzbekistan ~ 60 > one of the tragic incidents occurred at the end of 2022 in Samarkand. Doctors raised the alarm after they began to notice a sharp increase in the number of children with symptoms of acute renal failure. As a result of the investigation, it turned out that the two painkillers and antipyretic syrup imported from India were polluted by ethylene glycol or dietilenlycol. In January 2023, WHO released a warning No. 1/2023 on 21 batch of these drugs. & nbsp; As a result of poisoning, 68 people died, most of them are children. This has become one of the largest registered incidents of drug pollution & NBSP; Deg/EG in recent years. The authorities of Uzbekistan found that the distributor, representing the interests of the manufacturer, paid bribes to officials and health care officers to accelerate registration, promotion and increase in sales of these drugs. In particular, a bribe of 33 thousand dollars was transferred to one of the officials in order to avoid checking products. vulnerabilities of the chain supply The report emphasizes that the main threat lies in a vulnerable and poorly adjustable international chain of supplies of pharmaceutical excipients. Pollution of medicines is often the result of deliberate criminal acts. Organized criminal groups use the instability of the market and the weakness of regulation: they falsify documents, replace the raw materials & nbsp; and use digital platforms for the distribution of hazardous substances. also established cases of corruption when representatives of state bodies contributed to the release of such drugs on markets. 60 > according to the study, in most countries where incidents have occurred, there are no reliable systems for tracking the origin of the components, and in some cases the laboratory is not able to & nbsp; identify toxins: even if testing may be carried out, the results may be falsified. recommendations 60 > owed UNP and UNP is called up to decisive UNP actions: 60 ~ ul >~ 60 > tight control, testing and deliveries of auxiliary substances. 62 ~~ 60 > introduce the mandatory trace of the origin of all parties raw materials. ~ 60 > increase the responsibility of manufacturers and distributors. 60 > strengthen cooperation between regulatory authorities, law enforcement agencies and customs. ~ 60 > criminal liability for intentional pollution and falsification. ~ ul > 60 > also recommended use of the UN Convention against Transnational Organized Crime for Crime A cross -border investigation of such crimes. ~ 60 > report emphasizes: polluted drugs – & nbsp; not an accident, but a symptom of systemic problems. Without immediate measures of the tragedy, like what happened in Uzbekistan, they will be repeated, warned in UN institutions.